Search This Blog

1

Labels

Cancer (150) Breast (38) Study (38) Health (32) Patients (31) Treatment (27) Could (23) Therapy (19) Research (17) Against (12) Blood (11) Disease (11) linked (11) Diabetes (10) Early (10) Prevent (10) Survival (10) Treatments (7) higher (7) surgery (7) Might (6) Prostate (6) Tumors (6) During (5) Effects (5) Growth (5) Chemotherapy (4) Drinking (4) Prevention (4) Obama (3) Obesity (3) Without (3) associated (3) Experts (2) Important (2) Infection (2) About (1) Analysis (1) Causes (1) Eliminate (1) stroke (1)

AD

Showing posts with label Small. Show all posts
Showing posts with label Small. Show all posts

Tuesday, January 7, 2014

RAMBO a small but powerful magnet: System allows high-magnetic-field experiments on a tabletop

Jan. 6, 2014 — Rice University scientists have pioneered a tabletop magnetic pulse generator that does the work of a room-sized machine -- and more.

The device dubbed "RAMBO" -- short for Rice Advanced Magnet with Broadband Optics -- will allow researchers who visit the university to run spectroscopy-based experiments on materials in pulsed magnetic fields of up to 30 tesla. (A high-resolution magnetic resonance imaging system is about 10 tesla in strength.)

The Rice lab of physicist Junichiro Kono created RAMBO in collaboration with Hiroyuki Nojiri at the Institute for Materials Research at Tohoku University in Sendai, Japan. Details appeared online recently in the American Institute of Physics journal Review of Scientific Instruments.

The advantages of such a small machine are many, said Timothy Noe, a postdoctoral research associate in Kono's group and lead author of the paper. Aside from its size and powerful performance, RAMBO has windows that allow researchers to directly send a laser beam to the sample and collect data at close range.

"We can literally see the sample inside the magnet," Kono said. "We have direct optical access, whereas if you go to a national high magnetic field facility, you have a monster magnet, and you can only access the sample through a very long optical fiber. You cannot do any nonlinear or ultrafast optical spectroscopy.

"RAMBO finally gives us the ability to combine ultrastrong magnetic fields and very short and intense optical pulses. It's a combination of two extreme conditions."

The device's unique configuration allows for the best access ever in a powerful magnetic field generator meant for scientific experimentation. Researchers can collect real-time, high-resolution data in a system that couples high magnetic fields and low temperatures with direct optical access to the magnet's core, Kono said.

In addition, the unit can run a new experiment in a 30-tesla field every 10 minutes (or less for smaller peak fields), as opposed to waiting the hours often required for field generators to cool down after each experiment at large laboratories.

The device has already paid dividends for Kono's group, which studies superfluorescence by hitting materials with femtosecond laser pulses to trigger quantum effects. RAMBO allows the laser pulse, the magnetic field pulse and the spectrometer to work in sync.

RAMBO is possible, he said, because of Nojiri's development of a small and light mini-coil magnet. A little bigger than a spool of thread, the magnet allows Rice researchers to perform on campus many of the experiments they once carried out at the National High Magnetic Field Laboratory at Florida State University or at Los Alamos National Laboratory.

The Florida State facility has produced continuous magnetic fields of 45 tesla; Los Alamos has produced pulses over 100 tesla.

"I would say we've been able to do 80 percent of the experiments here that we used to have to do elsewhere," Kono said. "And that's not all. There are things that only we can do here. This is a unique system that doesn't exist anywhere else in the world.

"High magnetic fields have been around for many years. Ultrafast spectroscopy has been around for many years. But this is the first combination of the two," he said.

Kono's group built the system to analyze very small, if not microscopic, samples. A sample plate sits on a long sapphire cylinder that passes through the coil's container and juts through one end of the magnet to place it directly in the center of the magnetic field.

The cylinder provides one direct window to the experiment; a port on the other side of the container looks directly down upon the sample. The coil is bathed in liquid nitrogen to keep it cool at around 80 kelvins (-315 degrees Fahrenheit). The sample temperature can be independently controlled from about 10 K to room temperature by adjusting the flow of liquid helium to the sapphire cylinder.

Kono said he expects RAMBO to make Rice one center of an international network of researchers working on modern materials. "This opens up all kinds of possibilities," he said. "Scientists working in different areas will come up with new ideas just by knowing such a thing is possible."

He said the team has already collaborated with Jean Leotin, a co-author of the paper and a professor at the Laboratoire National des Champs Magnetiques Intenses in Toulouse, France, to perform one of the first time-domain terahertz spectroscopy experiments in high magnetic fields.

Co-authors include Joseph Lee, a student at Clements High School, Sugar Land, Texas, who works in Kono's lab, and Gary Woods, a professor in the practice of computer technology and electrical and computer engineering.

The National Science Foundation, the Department of Energy and the Robert A. Welch Foundation supported the research.


View the original article here

Monday, September 16, 2013

Binge drinkers' 'small baby' risk

Pregnant woman holding wine glassThe Born in Bradford study found binge drinking increased the risk of having a small baby

Women who binge drink in the second three months of pregnancy are 68% more likely to have a small baby, research has shown.

Doctors studied the drinking habits of 11,000 mothers in Bradford between 2007 and 2011, as part of the Born in Bradford (BiB) project.

They found more than 40% drank alcohol while pregnant, and 333 women continued to binge drink.

But low or moderate levels of drinking did not increase the risk.

The effects of alcohol in pregnancy

  • When a pregnant woman drinks alcohol, the levels of alcohol in her baby's blood rise as high as her own
  • When an unborn baby is constantly exposed to alcohol, a particular group of problems can develop, known as foetal alcohol syndrome
  • The government advises pregnant women to avoid alcohol completely, although if they do choose to drink, it says not to have more than one to two units of alcohol once or twice a week.
  • The Royal College of Obstetricians and Gynaecologists says there is no evidence a couple of units once or twice a week will harm the baby. Binges, even if you do not do it regularly, are definitely to be avoided

Source: BBC Health

The researchers defined binge drinking as having at least five units of alcohol in a short space of time - about half a bottle of wine, or two pints of beer.

The government recommends that pregnant women should avoid alcohol altogether but if they do drink, to limit it to one to two units of alcohol no more than twice a week.

'Significant risks'

Lead report author Dr Duncan Cooper said: "Growth-restricted babies have a greater risk of various neonatal complications including breathing problems, respiratory infections and hypothermia and impaired neurodevelopment.

"Our findings support government policy that while there is no risk from drinking small amounts of alcohol during pregnancy, women should not binge drink as there are significant risks and consequences for their unborn child."

The study found no relationship though between binge drinking and premature birth.

Professor John Wright, head of the BiB project, said: "Alcohol consumption during pregnancy is a contentious topic but this research demonstrates a clear link between binge drinking during pregnancy and having a small baby.

"There are various services locally in Bradford and across the country to help women cut down or stop drinking, or deal with alcohol dependency, but the best place for women to start discussing these issues is with their GP or midwife."

Born in Bradford began in 2007 and aims to look at every aspect of a child's development to try to get an idea of how factors like environment, education, diet, ethnicity and genes interact together to affect health.


View the original article here